The University of Chicago Medication is a scholastic medical center, a hospital where physicians and researchers are investigating the latest treatments and finding tomorrow’s medical advancements. We are proud to be home to among the oldest National Institutes of Health-funded cardiovascular research study programs in the nation. Our physician-scientists benefit from millions of dollars in annual research support to study heart disease. We likewise train tomorrow’s scientists with our NIH cardiovascular training program.
All of our heart specialists are studying brand-new methods to identify and deal with heart issues, from cutting edge tests and advanced drug therapies, to sophisticated life-saving surgical procedures. In addition, a lot of our physician-scientists are analyzing basic questions in molecular biology, physiology, pharmacology and biochemistry, which, in turn, helps set the structure for unique treatments for numerous forms of heart disease. Clients benefit from research study therapies such as using cancer drugs to deal with pulmonary hypertension, gene therapy and next-generation ventricular help devices for heart failure, and advanced stenting to treat aortic aneurysms.
Early Access to New Therapies
Our focus on translational research study – or “bench to bedside” medicine – implies that our scientists are working to speed the rate at which brand-new biomedical discoveries are put to efficient use in client care. Because of this requirement of development, University of Chicago Medicine heart professionals can often use treatments long before they are readily available somewhere else.
Our cardiologists and cardiac cosmetic surgeons are always conducting scientific trials of new drug treatments, surgical procedures, heart gadgets, imaging strategies and more.
View a partial list of heart medical trials under way
Medical Research Study Emphasizes
Below is simply a list of a few of the current medical research study completed or under way at the University of Chicago Medicine:
- Electro physiologists here are investigating numerous kinds of brand-new implantable gadgets to treat heart rhythm problems, including an absolutely subcutaneous implantable defibrillator to prevent abrupt heart death, heart resynchronization therapy for clients with heart failure, and making use of remote tracking gadgets.
- Our heart transplant group took part in a medical trial of the Transmedic Organ Care System, a device that is developed to keep the heart pounding while in transit for hair transplant, leading to much better preservation of donor hearts.
- University of Chicago cosmetic surgeons and heart surgeons collaborated to develop and improve a technique – called sternal plating – that strengthens the breast bone after heart surgery. Given that embracing this technique to close the breast bone in high-risk clients, our cosmetic surgeons have actually observed a dramatic decrease in pain, length of time to resume typical activity and the incidence of post-operative infections.
- Interventional cardiologists are studying several aspects of treatment for coronary artery illness and peripheral vascular illness, as well as devices for closure of heart flaws. New anti-coagulant drugs, drug eluting stents and devices to prevent blood clots in clients with atrial fibrillation who take warfarin are under examination.
- Cardiac arrest specialists are investigating new strategies to discover heart transplant rejection, brand-new drugs for cardiac arrest and gadgets that constantly keep track of heart pressures for much better management of heart failure on an outpatient basis.
- Our interventional cardiologists and electro physiologists use the Stereo taxis magnetically assisted system to move catheters through the heart with no danger of puncture and with the benefit of regulated motion offered by a GPS-like navigation system.
- We are one of 17 U.S. organizations taking part in a medical trial of the Heart Ware HVAD left ventricular help gadget (LVAD). This next generation LVAD supplies cardiac arrest clients with as much as 10 liters of extra blood circulation, bring back lifestyle in many cases. The implantable device is only the size of a D-cell battery.
- Several heart ablation trials for arrhythmias are under way, checking out alternative ablation tools such as cryoenergy, irrigated ablation electrodes, and bipolar ablation catheters to treat atrial fibrillation.
- University of Chicago heart surgeons originated new approaches to reducing the risk for kidney injury throughout surgical treatment, including refining methods for perioperative hemofiltration. Our cardiac surgical treatment team is taking part in a phase I clinical trial to identify the security and effectiveness of a new drug and its capability to minimize the occurrence of acute kidney injury following cardiac surgery.
- Cardiac imaging professionals are applying the latest imaging innovations, including three-dimensional echocardiography, heart magnetic resonance imaging (MRI) and 256-slice CT angiography – to evaluate heart function and to much better plan treatment.
Standard Science Medical research Study
Fundamental science medical research looks into fundamental concerns, such as observing disease at a molecular level or comprehending how cells communicate with each other. Understanding gained from standard science medical research study is vital to the advancement of new treatments. At the University of Chicago, medical researchers performing studies in cardiac standard science medical research study team up with other medical researchers on campus and somewhere else to speed clinical progress. Some examples of this medical research consist of the following:
- Mahesh Gupta, PhD, is checking out the molecular basis of cardiac arrest, particularly the role of chromatin remodeling enzymes in gene deregulation, contractile dysfunction and cell death throughout cardiac arrest.
- Marion Hoffman, MD, PhD, is exploring the basis of atherosclerosis in blood vessels like the aorta. Her medical research studies are recognizing novel inflammatory paths that drive arterial disease, which may provide new healing targets.
- Jim Holaska, PhD, is a basic medical researcher studying muscle illness and has determined the function of the nucleus in triggering some types of heart and skeletal muscle disease.
Dorothy Hanck, PhD, is concentrating on heart ion channel biophysics, physiology and pharmacology with the objective of determining heart-specific characteristics and their structural basis that can be used to direct drug style.